Healthcare News

The Management Of Renal Cell Carcinoma In The Elderly: Physiologic Age Wins Out Over Chronologic Age

March 09, 2017

UroToday - The median age of presentation for patients with renal cell carcinoma (RCC) is in the 6th decade of life, but urologists are not uncommonly confronted with an elderly patient (>=75 years of age) with a renal mass seeking treatment. As the population ages, co-morbidities become more confounding in predicting patient outcome to therapy, and may influence the application of surgical therapy with curative intent to elderly patients. In this study by Berdjis and colleagues out of Germany, the outcome of elderly patients (defined as >=75 years of age) is examined relative to a younger patient cohort.

Over a 10 year period, 1023 patients underwent radical or partial nephrectomy for RCC at a single institution. Of these, 115 patients were >=75 years of age. Patients in the older cohort had a higher incidence of co-morbid conditions, as evidenced by their higher American Society of Anesthesia (ASA) scores (p